summaryrefslogtreecommitdiff
path: root/R
diff options
context:
space:
mode:
Diffstat (limited to 'R')
-rw-r--r--R/WP_internal.R106
1 files changed, 106 insertions, 0 deletions
diff --git a/R/WP_internal.R b/R/WP_internal.R
new file mode 100644
index 0000000..54744b9
--- /dev/null
+++ b/R/WP_internal.R
@@ -0,0 +1,106 @@
+#' WP method background function WP_known
+#'
+#' This is a background/internal function called by \code{WP}. It computes the maximum
+#' likelihood estimator of R0 assuming that the serial distribution is known and finite discrete.
+#'
+#' @param NT Vector of case counts.
+#' @param p Discretized version of the serial distribution.
+#'
+#' @return The function returns the maximum likelihood estimator of R0.
+#'
+#' @keywords internal
+WP_known <- function(NT, p) {
+ k <- length(p)
+ TT <- length(NT) - 1
+ mu_t <- rep(0, TT)
+
+ for (i in 1:TT) {
+ Nt <- NT[i:max(1, i-k+1)]
+ mu_t[i] <- sum(p[1:min(k, i)] * Nt)
+ }
+
+ Rhat <- sum(NT[-1]) / sum(mu_t)
+ return(Rhat)
+}
+
+#' WP method background function WP_unknown
+#'
+#' This is a background/internal function called by \code{WP}. It computes the maximum likelihood estimator
+#' of R0 assuming that the serial distribution is unknown but comes from a discretized gamma distribution.
+#' The function then implements a simple grid search algorithm to obtain the maximum likelihood estimator
+#' of R0 as well as the gamma parameters.
+#'
+#' @param NT Vector of case counts.
+#' @param B Length of grid for shape and scale (grid search parameter).
+#' @param shape.max Maximum shape value (grid \code{search} parameter).
+#' @param scale.max Maximum scale value (grid \code{search} parameter).
+#' @param tol cutoff value for cumulative distribution function of the serial distribution (defaults to 0.999).
+#'
+#' @return The function returns \code{Rhat}, the maximum likelihood estimator of R0, as well as the maximum
+#' likelihood estimator of the discretized serial distribution given by \code{p} (the probability mass
+#' function) and \code{range.max} (the distribution has support on the integers one to \code{range.max}).
+#' The function also returns \code{resLL} (all values of the log-likelihood) at \code{shape} (grid for
+#' shape parameter) and at \code{scale} (grid for scale parameter), as well as \code{resR0} (the full
+#' vector of maximum likelihood estimators), \code{JJ} (the locations for the likelihood for these), and
+#' \code{J0} (the location for the maximum likelihood estimator \code{Rhat}). If \code{JJ} and \code{J0}
+#' are not the same, this means that the maximum likelihood estimator is not unique.
+#'
+#' @importFrom stats pgamma qgamma
+#'
+#' @keywords internal
+WP_unknown <- function(NT, B=100, shape.max=10, scale.max=10, tol=0.999) {
+ shape <- seq(0, shape.max, length.out=B+1)
+ scale <- seq(0, scale.max, length.out=B+1)
+ shape <- shape[-1]
+ scale <- scale[-1]
+
+ resLL <- matrix(0,B,B)
+ resR0 <- matrix(0,B,B)
+
+ for (i in 1:B) {
+ for (j in 1:B) {
+ range.max <- ceiling(qgamma(tol, shape=shape[i], scale=scale[j]))
+ p <- diff(pgamma(0:range.max, shape=shape[i], scale=scale[j]))
+ p <- p / sum(p)
+ mle <- WP_known(NT, p)
+ resLL[i,j] <- computeLL(p, NT, mle)
+ resR0[i,j] <- mle
+ }
+ }
+
+ J0 <- which.max(resLL)
+ R0hat <- resR0[J0]
+ JJ <- which(resLL == resLL[J0], arr.ind=TRUE)
+ range.max <- ceiling(qgamma(tol, shape=shape[JJ[1]], scale=scale[JJ[2]]))
+ p <- diff(pgamma(0:range.max, shape=shape[JJ[1]], scale=scale[JJ[2]]))
+ p <- p / sum(p)
+
+ return(list(Rhat=R0hat, J0=J0, ll=resLL, Rs=resR0, scale=scale, shape=shape, JJ=JJ, p=p, range.max=range.max))
+}
+
+#' WP method background function computeLL
+#'
+#' This is a background/internal function called by \code{WP}. It computes the log-likelihood.
+#'
+#' @param NT Vector of case counts.
+#' @param p Discretized version of the serial distribution.
+#' @param R0 Basic reproductive ratio.
+#'
+#' @return This function returns the log-likelihood at the input variables and parameters.
+#'
+#' @keywords internal
+computeLL <- function(p, NT, R0) {
+ k <- length(p)
+ TT <- length(NT) - 1
+ mu_t <- rep(0, TT)
+
+ for (i in 1:TT) {
+ Nt <- NT[i:max(1, i-k+1)]
+ mu_t[i] <- sum(p[1:min(k, i)] * Nt)
+ }
+
+ mu_t <- R0 * mu_t
+ LL <- sum(NT[-1] * log(mu_t)) - sum(mu_t)
+
+ return(LL)
+}