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authorTatiana Krikella <106450627+TKrikella@users.noreply.github.com>2024-11-14 13:01:01 -0500
committerGitHub <noreply@github.com>2024-11-14 13:01:01 -0500
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-This is a short description of the WP method.
+The White and Pagano (WP) estimator uses maximum likelihood estimation to estimate <em>R</em><sub>0</sub>.
+In this method, the serial interval (SI) is either known, or can be estimated along with <em>R</em><sub>0</sub>.
+It is assumed that the number of infectious individuals are observable at discrete time points (ie. daily or weekly).
+Further, this method also assumes an underlying branching process, which means that throughout, the population size “available” to be infected remains constant.
+We note that this assumption does not hold for the SIR/SEIR/SEAIR compartmental models.
+As such, WP estimates should only really be considered early on in an epidemic, ie. before the inflection point of an epidemic, if the dataset being used follows these models.